DJ-1 ELISA Kit

DJ-1 ELISA Kit 

Catalog Number: DJ1-01-1054

Size: 1 plate (96 wells)

DJ-1 ELISA Kit is a sandwich enzyme-linked immunoassay for the quantitative determination of DJ-1 with high sensitivity and specificity in serum or plasma.

Kit Performance

• Sensitivity: 0.1 ng/mL
• Assay Range: 0.1 – 20 ng/mL
• Cross-reactivity: There is no cross reaction with native immunoglobulins
• Recovery rate: 80 – 120% with normal human serum, plasma or CSF samples with known concentrations.
• Precision

(CV (%) = SD/mean X 100)

• Intra-Assay: CV < 20%
• Inter-Assay: CV < 20%

Materials Supplied

List of component

Storage Instruction

The components arrive with ice pack, and must immediately be stored at 2-8°C. The kit components are stable at the date specified in CoA.

Supplementary information

DJ-1 (also known as PARK7) is a multifunctional protein involved in cellular protection against oxidative stress. It is expressed in many tissues, including the brain, heart, and skeletal muscle, and plays an important role in maintaining cell survival and mitochondrial function.

DJ-1 functions mainly as a sensor and regulator of oxidative stress. When cells are exposed to reactive oxygen species (ROS), DJ-1 helps protect them by scavenging oxidative molecules, regulating antioxidant responses, and stabilizing mitochondrial activity. Through these actions, DJ-1 helps maintain cellular redox balance and protects cells from damage.

DJ-1 is particularly important in neurons, where it contributes to protecting dopaminergic neurons from oxidative injury. Mutations in the PARK7 gene, which encodes DJ-1, have been linked to familial forms of Parkinson’s disease.