sCD22 (Human) ELISA Kit

sCD22 (Human) ELISA Kit 

Catalog Number: SCD22-01-1027

Size: 1 plate (96 wells)

CD22 ELISA Kit is a sandwich enzyme-linked immunoassay for the quantitative determination of CD22 with high sensitivity and specificity in serum or plasma.

Kit Performance

• Sensitivity: 5 ng/mL
• Assay Range: 5 – 100 ng/mL
• Cross-reactivity: There is no cross reaction with native immunoglobulins
• Recovery rate: 80 – 120% with normal human serum or plasma samples with known concentrations.
• Precision

(CV (%) = SD/mean X 100)

• Intra-Assay: CV < 20%
• Inter-Assay: CV < 20%

Materials Supplied

List of component

Storage Instruction

The components arrive with ice pack, and must immediately be stored at 2-8°C. The kit components are stable at the date specified in CoA.

Supplementary information

Soluble CD22 (sCD22) is a circulating form of CD22, a B-cell–specific transmembrane glycoprotein belonging to the Siglec (sialic acid–binding immunoglobulin-like lectin) family. sCD22 is generated through proteolytic shedding or release from B cells and can be detected in serum or plasma.

CD22 normally functions as an inhibitory co-receptor of the B-cell receptor (BCR) that regulates B-cell activation and maintains immune tolerance. The soluble form reflects B-cell activation or turnover and has been investigated as a biomarker in B-cell–related diseases, including autoimmune disorders and B-cell malignancies.