TACI (Human) ELISA Kit

TACI (Human) ELISA Kit 

Catalog Number: TACI-01-1027

Size: 1 plate (96 wells)

TACI ELISA Kit is a sandwich enzyme-linked immunoassay for the quantitative determination of TACI with high sensitivity and specificity in serum, plasma or CSF.

Kit Performance

• Sensitivity: 50 pg/mL
• Assay Range: 50 – 1000 pg/mL
• Cross-reactivity: There is no cross reaction with native immunoglobulins
• Recovery rate: 80 – 120% with normal human serum, plasma or CSF samples with known concentrations.
• Precision

(CV (%) = SD/mean X 100)

• Intra-Assay: CV < 20%
• Inter-Assay: CV < 20%

Materials Supplied

List of component

Storage Instruction

The components arrive with ice pack, and must immediately be stored at 2-8°C. The kit components are stable at the date specified in CoA.

Supplementary information

TACI (Transmembrane Activator and CAML Interactor), also known as TNFRSF13B, is a receptor in the tumor necrosis factor receptor (TNFR) superfamily that regulates B-cell activation, maturation, and antibody production.

TACI binds the ligands APRIL (TNFSF13) and BAFF (TNFSF13B), transmitting signals that promote B-cell survival, immunoglobulin class switching, and plasma cell differentiation.

TACI is primarily expressed on mature B cells, activated B cells, and plasma cells. Mutations in TNFRSF13B are associated with immunodeficiency disorders such as common variable immunodeficiency (CVID) and can affect normal antibody responses.