APRIL (Human) ELISA Kit

APRIL (Human) ELISA Kit 

Catalog Number: APRIL-01-1026

Size: 1 plate (96 wells)

APRIL ELISA Kit is a sandwich enzyme-linked immunoassay for the quantitative determination of APRIL with high sensitivity and specificity in serum, plasma or CSF.

Kit Performance

• Sensitivity: 30 pg/mL
• Assay Range: 30 – 1500 pg/mL
• Cross-reactivity: There is no cross reaction with native immunoglobulins
• Recovery rate: 80 – 120% with normal human serum, plasma or CSF samples with known concentrations.
• Precision

(CV (%) = SD/mean X 100)

• Intra-Assay: CV < 20%
• Inter-Assay: CV < 20%

Materials Supplied

List of component

Storage Instruction

The components arrive with ice pack, and must immediately be stored at 2-8°C. The kit components are stable at the date specified in CoA.

Supplementary information

APRIL (A Proliferation-Inducing Ligand), also known as TNFSF13, is a cytokine in the tumor necrosis factor (TNF) superfamily that regulates B-cell survival, proliferation, and antibody production. It primarily signals through the receptors TACI (TNFRSF13B) and BCMA (TNFRSF17).

APRIL is produced by monocytes, macrophages, dendritic cells, T cells, neutrophils, and some tumor cells. Elevated APRIL levels are associated with autoimmune diseases (e.g., systemic lupus erythematosus, rheumatoid arthritis) and B-cell malignancies such as multiple myeloma and lymphoma.