IL-6 ELISA Kit

IL-6 ELISA Kit 

Catalog Number: IL6-01-1031

Size: 1 plate (96 wells)

IL-6 ELISA Kit is a sandwich enzyme-linked immunoassay for the quantitative determination of IL-6 with high sensitivity and specificity in serum or plasma.

Kit Performance

• Sensitivity: 1 pg/mL
• Assay Range: 1 – 50 pg/mL
• Cross-reactivity: There is no cross reaction with native immunoglobulins
• Recovery rate: 80 – 120% with normal human serum or plasma samples with known concentrations.
• Precision

(CV (%) = SD/mean X 100)

• Intra-Assay: CV < 20%
• Inter-Assay: CV < 20%

Materials Supplied

List of component

Storage Instruction

The components arrive with ice pack, and must immediately be stored at 2-8°C. The kit components are stable at the date specified in CoA.

Supplementary information

IL-6 (Interleukin-6) is a cytokine that plays an important role in inflammation and immune regulation.

IL-6 is released by several cell types, including macrophages, T cells, B cells, endothelial cells, fibroblasts, adipocytes, and muscle cells. Its production is typically triggered by pathogen signals, tissue damage, or other pro-inflammatory cytokines such as IL-1β and TNF-α.

After being released, IL-6 binds to the IL-6 receptor (IL-6R) and the co-receptor gp130 on target cells. This activates intracellular pathways, mainly JAK/STAT signaling, which transmit the inflammatory signal to the cell.